Tag: Pakistan

• Myriad Genetics’ EndoPredict test accurately identified premenopausal women with ER+, HER2- breast cancer who could safely avoid adjuvant chemotherapy

SALT LAKE CITY, Aug. 31, 2022 (GLOBE NEWSWIRE) — Myriad Genetics, Inc. (NASDAQ: MYGN), a leader in genetic testing and precision medicine, announced today Clinical Cancer Research, a journal of the American Association for Cancer Research, published a study ¹ that shows the EndoPredict^® breast cancer prognostic test significantly predicted distant recurrence in premenopausal women with ER+, HER2- early-stage breast cancer. This newly published study represents the first clinical validation of EndoPredict in a solely premenopausal population.

The study — first presented in an abstract at the 2021 ASCO Annual Meeting by Anastasia Constantinidou et al² — examined tumor samples from 385 premenopausal women with ER+, HER2- primary breast cancer who had not received chemotherapy. The results show EndoPredict accurately identified premenopausal women with and without affected lymph nodes who could safely avoid adjuvant chemotherapy as part of their treatment plans due to a very low recurrence risk.

“This important publication on the new EndoPredict data demonstrates our ongoing commitment to advance precision medicine for patients with breast cancer,” said Dr. Ralf Kronenwett, director of International Medical Affairs, Myriad Genetics. “In light of mounting clinical recommendations to reduce overtreatment in breast cancer, the results are particularly encouraging. With around a third of all new breast cancer cases occurring in patients aged 54 or younger³, using EndoPredict among premenopausal women provides important insights to inform personalized treatment, including whether there’s a benefit to using chemotherapy or not.”

The study shows that patients with EndoPredict low-risk scores had a 97% distant recurrence free survival (DRFS) versus 76% for high-risk patients. Importantly, 19% of node-positive premenopausal patients had EndoPredict low-risk scores with 100% DRFS and were able to safely avoid chemotherapy and continue onto endocrine therapy alone.

Another key result from an exploratory subgroup analysis within the study found similar DRFS rates in low-risk patients with or without ovarian function suppression (OFS), with less than 5% distant recurrence after 10 years in both groups.

“This important study shows that premenopausal patients with a low-risk EndoPredict score have a good long-term outcome without chemotherapy and may be considered for treatment with endocrine therapy only,” said Dr. Anastasia Constantinidou, Bank of Cyprus Oncology Centre and Cyprus Cancer Research Institute. “These findings are relevant to better inform personalized treatment decisions for a large proportion of premenopausal women with ER+, HER2- early-stage breast cancer.”

About the study
EndoPredict is a prognostic test that predicts patient risk of breast cancer recurrence to help identify who can consider safely forgoing chemotherapy. It analyzes 12 genes to create a molecular score, which is combined with tumor features, such as tumor size and nodal status, to establish a patient risk score (EPclin).

The Clinical Validation of EndoPredict in Premenopausal Women study tested tumor samples from 385 premenopausal women with ER+, HER2- primary breast cancer (pT1-3, pN0-1) who did not receive chemotherapy in addition to endocrine therapy. All samples were retrospectively tested blinded to clinical and outcome data with EndoPredict. Associations of EPclin Risk Scores with 10-year DRFS were evaluated by Cox proportional hazards models and Kaplan-Meier analysis. The primary outcome was 10-year DRFS.

In addition to EPclin, clinical variables of interest included age at diagnosis, tumor size, tumor grade, nodal status, Ki 67 expression, and continuous estrogen receptor (ER) expression and progesterone receptor (PgR) expression.

More information about this study can be found here.

¹ Constantinidou et al. Clin Cancer Res 2022 (https://aacrjournals.org/clincancerres/article/doi/10.1158/1078-0432.CCR-22-0619/708058/Clinical-Validation-of-EndoPredict-in)
² Constantinidou et al 2021 ASCO (https://ascopubs.org/doi/abs/10.1200/JCO.2021.39.15_suppl.537)
³ SEER Cancer Statistics Review, 1975-2016. Bethesda, MD: National Cancer Institute;2019.

About Myriad Genetics
Myriad Genetics is a leading genetic testing and precision medicine company dedicated to advancing health and well-being for all. Myriad develops and offers genetic tests that help assess the risk of developing disease or disease progression and guide treatment decisions across medical specialties where genetic insights can significantly improve patient care and lower healthcare costs. Fast Company named Myriad among the World’s Most Innovative Companies for 2022. For more information, visit www.myriad.com.

Myriad, the Myriad logo, BRACAnalysis, BRACAnalysis CDx, Colaris, Colaris AP, MyRisk, Myriad MyRisk, MyRisk Hereditary Cancer, MyChoice CDx, Prequel, Prequel with Amplify, Amplify, Foresight, Precise, FirstGene, Health.Illuminated., RiskScore, Prolaris, GeneSight, and EndoPredict are trademarks or registered trademarks of Myriad Genetics, Inc. © 2022 Myriad Genetics, Inc. All rights reserved.

Safe Harbor Statement
This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including statements relating to using EndoPredict among premenopausal women to provide important insights to inform personalized treatment, including whether there’s a benefit to using chemotherapy or not. These “forward-looking statements” are management’s expectations of future events as of the date hereof and are subject to a number of known and unknown risks and uncertainties that could cause actual results, conditions, and events to differ materially and adversely from those anticipated. Such factors include those risks described in the company’s filings with the U.S. Securities and Exchange Commission, including the company’s Annual Report on Form 10-K filed on February 25, 2022, as well as any updates to those risk factors filed from time to time in the company’s Quarterly Reports on Form 10-Q or Current Reports on Form 8-K.

Media Contact: Megan Manzari (385) 318-3718 Megan.Manzari@myriad.com

Investor Contact: Foster Harris (385) 350-8015 Foster.Harris@myriad.com

COPENHAGEN, Denmark, Aug. 31, 2022 (GLOBE NEWSWIRE) — Copenhagen Infrastructure Partners (CIP) has reached final close on its new fund, CI Energy Transition Fund I (CI ETF I). The fund was oversubscribed and closed at the hard cap of EUR 3 billion. This makes CI ETF I the largest dedicated clean hydrogen fund globally.

CI ETF I achieved commitments from investors across the Nordics (~25% of commitments), Europe (~45%), Asia-Pacific (~20%) and North America (~10%) with approximately a 50/50 split between existing investors in CIP funds and new investors. The fund’s investor base comprises approximately 65 institutional investors, primarily pension funds, life insurance companies, sovereign wealth funds, asset managers, and family offices.

“We are very pleased to welcome a prominent group of existing and new institutional investors to CI ETF I and are delighted that investors share our confidence in and appetite for clean energy infrastructure projects and invest alongside CIP in the next phase of the energy transition. Solutions such as Power-to-X will be key for countries and industries to take the next big leap within reaching the commitments of the Paris agreement and achieving energy independence. As an industry pioneer and one of the global market leaders in greenfield renewable infrastructure investments, CIP is uniquely positioned to invest in this segment,” says Jakob Baruël Poulsen, Managing Partner in CIP.

CI ETF I will invest in next generation renewable energy infrastructure including industrial scale Power-to-X (PtX) projects and enables institutional investors to participate in the decarbonization of the so-called hard to abate industries and support the further integration of renewable power generation in the energy mix through grid balancing. The fund will primarily focus on greenfield projects in the OECD and aims to contribute to the decarbonization of industries such as agriculture, aviation, shipping, chemical manufacturing, and steel production through the use of green fuels and feedstock and CO2-free fertilizers.

CI ETF I make up an integral part of CIP’s distinct fund strategies that tap into the main renewable energy transition trends. The fund will apply the same and proven value creation and de-risking approach as CIP’s existing funds, though with a focus for CI ETF on PtX. CI ETF I will apply CIP’s industrial skills to optimize and de-risk its projects through among others project design, partner selection, and contracting. Once de-risked the projects are expected to have core infrastructure characteristics including long term offtake contracts.

CI ETF I is off to a strong start with FID taken on one investment and ownership on several attractive industrial scale development stage PtX projects with diverse exposure to production technologies and offtake markets. The projects which among others are in Western Europe (Denmark, Norway, Spain, Portugal), South America (Chile), and Australia are expected to produce green hydrogen, green ammonia, and sustainable aviation fuel based on GW scale renewable energy production and electrolysis capacity.

CI ETF I’s current portfolio once operational is estimated to reduce more than 7.5 million tonnes of CO2 annually (or the equivalent to removing ~1.6 million cars from the roads permanently) and deliver more than 4 million tonnes of green fuels each year.

For the marketing of CI ETF I, law firms Plesner and Clifford Chance acted as legal counsel, KPMG Acor Tax as tax advisor, and Selinus Capital Advisors, Compagnie Financière Jacques Coeur (CFJC) and Allen Partners as placement agents.

About Copenhagen Infrastructure Partners
Founded in 2012, Copenhagen Infrastructure Partners P/S (CIP) today is the world’s largest dedicated fund manager within greenfield renewable energy investments and a global leader in offshore wind. The funds managed by CIP focuses on investments in offshore and onshore wind, solar PV, biomass and energy-from-waste, transmission and distribution, reserve capacity, storage, advanced bioenergy, and Power-to-X.

CIP manages ten funds and has to date raised approximately EUR 19 billion for investments in energy and associated infrastructure from more than 135 international institutional investors. CIP will accelerate its role in the global energy transition and aim to have EUR 100 billion under management in green energy investments in 2030. CIP has approximately 340 employees and offices in Copenhagen, London, Hamburg, Utrecht, New York, Tokyo, Singapore, Seoul, and Melbourne. For more information, visit www.cip.dk

For further information, please contact:

Simon Augustesen, – VP, Chief Communication and Marketing Officer, Phone: +45 30526721, Email: siau@cip.dk

Thomas Kønig, Partner – Investor Relations, Phone: +45 7070 5151, Email: tkon@cip.dk

QUEBEC CITY, Aug. 31, 2022 (GLOBE NEWSWIRE) — LeddarTech^®, a global leader in providing the most flexible, robust and accurate ADAS and AD sensing technology, proudly announces receiving two awards recognizing its LeddarVision sensor fusion and perception platform. The platform is a flexible, robust, cost-effective, sensor-agnostic and scalable auto-grade solution that delivers highly accurate 3D environmental models. In addition, the software supports all SAE autonomy levels by applying AI and computer vision algorithms to fuse raw data from sensors employed in L2-L5 on-road and off-road autonomous vehicle applications.

Tel Aviv, Israel, May 2022 – The Volkswagen Group Innovation Tel Aviv 2022 Konnect and CARIAD Startup Challenge awarded LeddarTech with a cash prize for its sensor fusion and perception technology

“We were impressed by LeddarTech’s professionally prepared pitch and proposal of a PoC,” stated Jan Zawadzki, Head of AI, CARIAD. “We were intrigued by their technical capabilities, which fit our general ADAS strategy, and we’re looking forward to creating an AI safety-related PoC with their product,” Mr. Zawadzki concluded.

LeddarTech was selected in the final round of the competition after Konnect, the Open Innovation Hub of the Volkswagen Group, and the VW Commercial Vehicles judges screened more than 30 Israeli startups.

CARIAD is responsible for building the leading tech stack for the automotive industry, aiming to create a new automotive experience and increase the innovation speed of Volkswagen Group to make the car a sustainable, safe and seamlessly connected mobility companion in a digital world.

Shenzhen, China, August 13, 2022 – The Shenzhen Automotive Electronics Industry Association recognizes LeddarTech with the Automotive Electronics Science and Technology Award for LeddarVision in the Product Innovation Excellence category

LeddarTech received this award for its highly innovative raw data sensor fusion and perception technology that enhances ADAS and AD safety over traditional object fusion technology. This industry-first solution is also sensor agnostic and scalable, thus enabling its customers to scale up to Level 5 autonomy on the same platform. This commitment to a safer and more customer-centric sensor fusion and perception software solution sets LeddarTech apart, leading to being selected for this prestigious award.

The Shenzhen Automotive Electronics Industry Association was founded in 2010 as a non-profit organization with over 500 members representing auto electronics and related parts technology companies across China. The award recognizes scientific research and technological innovation in the auto electronics industry. The award-winning companies were determined after advanced engineering judges from the automotive industry and R&D experts from leading domestic automotive companies assessed more than 250 products.

“The recognition of our technology from these two organizations represents a profound acknowledgment of the expertise and challenging work of the sensor fusion and perception engineering teams led by our R&D center in Israel and our employees around the world who support these efforts,” stated Mr. Charles Boulanger, CEO of LeddarTech. “These awards are greatly appreciated and acknowledge our industry differentiation, commitment to win-win partnerships and, most importantly, our mission to enable ADAS and AD products that improve safety and the quality of life of drivers and the general public,” Mr. Boulanger concluded.

About LeddarTech

Founded in 2007, LeddarTech is a comprehensive end-to-end environmental sensing company that enables customers to solve critical sensing, fusion and perception challenges across the entire value chain. LeddarTech provides cost-effective perception solutions scalable from Level 2 ADAS to Level 5 full autonomy with LeddarVision, a raw-data sensor fusion and perception platform that generates a comprehensive 3D environmental model from a variety of sensor types and configurations. LeddarTech also supports LiDAR manufacturers and Tier 1-2 automotive suppliers with key technology building blocks such as LeddarSteer digital beam steering and LeddarEngine, which comprises a highly integrated, scalable LiDAR SoC and software combination that enables the accelerated design of automotive-grade LiDAR solutions with optimized cost-to-performance ratios. The company is responsible for several innovations in cutting-edge automotive and mobility remote-sensing applications, with over 140 patents granted or applied for, enhancing ADAS and autonomous driving capabilities.

Additional information about LeddarTech is accessible at www.leddartech.com and on LinkedIn, Twitter, Facebook and YouTube.

Contact:
Daniel Aitken, Vice-President, Global Marketing, Communications and Investor Relations, LeddarTech Inc.
Tel.: + 1-418-653-9000 ext. 232 daniel.aitken@leddartech.com

Investor relations contact: InvestorRelations@leddartech.com
https://investors.leddartech.com/

Leddar, LeddarTech, LeddarSteer, LeddarEngine, LeddarVision, LeddarSP, LeddarCore, LeddarEcho, VAYADrive, VayaVision, XLRator and related logos are trademarks or registered trademarks of LeddarTech Inc. and its subsidiaries. All other brands, product names and marks are or may be trademarks or registered trademarks used to identify products or services of their respective owners.

RIYADH, Saudi Arabia, Aug. 30, 2022 (GLOBE NEWSWIRE) — Falcon experts from breeding farms around the world have been singing the praises of this year’s International Saudi Falcons and Hunting Exhibition just two days into the event.

Now in its fourth year, the exhibition is larger than ever with visitation expected to top 500,000 over the course of the event, which runs from 25th August – 3rd September. Over 350 exhibitors are in attendance and many have shared their delight at the impact the exhibition is having on the industry.

Held at the Saudi Falcons Club HQ at Malham, attendees are greeted by the vast auditorium packed with falconry stalls, memorabilia, technology, equipment, photographs and items detailing the rich history of falconry in Saudi Arabia, including a huge stand showing the important work the Saudi Falcons Club does to promote the art of falconry and also the conservation of birds of prey. Namely with its Hadad project that helps the conservation of both two migratory falcons – the Saker falcon and the Peregrine falcon, along with the two resident birds, the Barbary falcon and the Lanner falcon.

International falcon breeders have been showcasing their stunning birds, with farms being represented from around the world. Numerous breeders from Europe include the UK’s Fox and Desert falcons, France’s SB Falcons and Hura Falcons from Belgium. From further afield, Sullivan Mews are attending from USA while more locally Gulf Falcons are in attendance from Bahrain.

French Breeder Philippe Hertel from SB Falcons said: “It’s my second participation at the exhibition and we are very proud and happy to have our farm here. For us it’s very important to be a part of the event as the business in Saudi Arabia there is a lot of falconers so of course we should be here to present our birds. We specialize in racing and so we have very fast falcons, we have had some winners in the past, so it’s important for the people here to see what we have to offer. The organization of the event is very good, from the shipping to the accommodation etc. It’s the best in the world compared to other events.”

German Breeder Ulf Voss from Voss Falcons said: “It’s the first time we are here, we are very happy to have been invited! We have 38 falcons with a great racing and hunting history. We try to bring the best racing falcons while making some great contacts for the future. We hope to increase our business with Saudi Arabia and so we are here getting our brand name out there to the people within the industry, it’s the most important thing for us right now. Saudi Arabia is the place to be for falconry at the moment and so it’s a really interesting market right now.”

Belgian Breeder Giel Van Haecke from Hura Falcons said: “It is very well organized, and it’s a great place for people to gather, connect and meet. You can’t get any better for the breeder, it’s a great place to sell birds and you need an event like this to make your name. Everyone is very friendly and there is a lot of different birds this year and when you breed quality there is no problem.”

The exhibition has a special section dedicated solely to the history of falconry both in Saudi Arabia and around the world. This area is full of interactive exhibits in place to educate and inspire the next generation of falconers in the Middle East. Other areas include an art gallery, featuring Saudi artist Hila Alhmod who is displaying a stunning Peregrine falcon, which has been created by pyrography. There is also an impressive auction hall for the daily falcon auctions. Education is a huge theme this year and experts are giving daily talks on the art of falconry, and there’s a big emphasis on encouraging the next generation of falconers through motivational speaking and children’s learning areas.

Now in its fourth year, the International Saudi Falcons and Hunting Exhibition 2022, has been welcoming visitors and exhibitors from over 30 participating countries, making it the biggest edition of the event thus far. The event, taking place in Riyadh, runs until 3rd September 2022.

Media Contact: Ahmad AlRefaie – +966 54 501 7470 – ahmad.alrefaie@xpotential-data.com

A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/0eaefc2d-f957-43a0-94c1-8429d510453f

LONDON, Aug. 30, 2022 (GLOBE NEWSWIRE) — Meco Limited (Mecobit) unveiled the much-anticipated Ultimate Solar Power System (a solar power system with amazing backups and cryptocurrency miners) at an elite launch event at the Hong Kong Technology Bureau in August 2020.Compact Solar Station Solar Panel Kit (Complete) Solar Array M4000 Highlights one of the most memorable solar powered crypto equipment in the world. Essential equipment that helps keep running or affects equipment such as appliances, dryers, pool siphons or electric car chargers, or even cryptocurrency mining equipment. We are looking for a boost from the global problems of fossil fuel by-products, high levels of electricity consumption. “It improves the way we approach imagination and planning. Moreover, make this progress reasonable for the customer,” said B. FRANCI, CEO of MECO LIMITED.

With the solar-focused part of the controlled hash rate seemingly easy to develop, many see the potential for sustainable electricity use in Bitcoin mining as a cycle of justice – Mecobit provides an extreme boost to cryptocurrency mining by enabling the mission to use sustainable electricity. The cheapest electricity imaginable will encourage more tasks to focus exclusively on environmentally friendly sources such as solar energy.

Key features of our miners:

⦁ Meco Rack:

Capacity: BTC-4850 TH/s, ETH/ETC-20000 MH/s

Calculation: SHA256, Ethash

8 x Nvidia RTX 3090 (includes warranty)

2 x Mining Frame/Shelf

3 x 930W 110-220V fully modular power supplies.

⦁ M100 miner:

Hash Rate: BTC 450TH/s, ETH/ETC 2000MH/s

Power: 1400 watts

Calculation: SHA256, Ethash

Connection: Ethernet/Wireless

⦁ M200 miner

Hash Rate: BTC 650 TH/s, ETH/ETC 2300 MH/s

Power: 1800 watts

Calculation: SHA256, Ethash

Connection: Ethernet/Wireless

About Mecobit

It was launched in 2015 with the determination to create and demonstrate to the world a solar-powered digital currency mine, and depending on the miner’s inclination, Ethash, SHA-256 or Scrypt innovations can be used. The organization says it is the absolute first solar-powered digital currency mining project on Earth. “We need to disrupt the solar charger business by providing more power at a more reasonable value than was recently thought to be the case.” – B. Franci (founder). Based on Chiswick High Road in London, UK, Mecobit has locations in various urban communities around the world, including the US. Additional information about the organization and its projects is available on the organization’s website www.mecobit.com

Contact: Ben Lukas, ben.lukas@mecobit.com, 852-3001 1453